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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DDX59
All Species:
32.42
Human Site:
S578
Identified Species:
47.56
UniProt:
Q5T1V6
Number Species:
15
Phosphosite Substitution
Charge Score:
0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q5T1V6
NP_001026895.2
619
68810
S578
L
P
P
Q
L
L
N
S
P
Y
L
H
D
Q
K
Chimpanzee
Pan troglodytes
XP_001143546
619
68778
S578
L
P
P
Q
L
L
N
S
P
Y
L
H
D
Q
K
Rhesus Macaque
Macaca mulatta
XP_001109688
319
35696
S278
L
P
P
Q
L
L
N
S
P
Y
L
H
D
Q
K
Dog
Lupus familis
XP_537128
620
68704
S579
L
P
P
Q
L
L
N
S
P
Y
L
H
D
Q
K
Cat
Felis silvestris
Mouse
Mus musculus
Q9DBN9
619
68216
S578
L
P
P
Q
L
L
N
S
P
Y
L
H
E
Q
K
Rat
Rattus norvegicus
Q66HG7
589
65047
S548
L
P
P
Q
L
L
N
S
P
Y
L
H
E
Q
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001520980
538
59378
S498
L
Q
G
I
S
L
Q
S
K
A
L
G
Y
E
V
Chicken
Gallus gallus
XP_422189
625
69278
S584
L
P
P
Q
L
L
N
S
P
Y
L
H
D
Q
K
Frog
Xenopus laevis
NP_001106297
254
27959
N214
E
K
N
Q
P
C
S
N
V
R
Q
I
V
L
W
Zebra Danio
Brachydanio rerio
Q4TVV3
1018
115121
L720
V
P
A
E
L
E
Q
L
W
T
N
F
K
E
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P09052
661
72313
F619
S
G
Q
T
V
P
D
F
L
R
T
C
G
A
G
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001198909
620
68882
S580
L
P
P
E
L
I
N
S
P
H
L
S
Y
H
R
Poplar Tree
Populus trichocarpa
XP_002320399
524
57616
P484
E
E
N
R
N
L
F
P
D
L
V
E
V
L
K
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q3EBD3
505
55199
D465
A
I
V
F
V
N
E
D
D
R
N
L
F
P
D
Baker's Yeast
Sacchar. cerevisiae
P24784
617
67899
L544
V
P
T
F
L
S
D
L
S
R
Q
N
S
R
G
Red Bread Mold
Neurospora crassa
Q7SEL0
728
82594
D676
F
L
G
P
E
D
N
D
V
L
Y
D
L
R
Q
Conservation
Percent
Protein Identity:
100
99
51
89.8
N.A.
83.6
79.8
N.A.
61.8
72.3
30.2
22.3
N.A.
27.6
N.A.
N.A.
32.1
Protein Similarity:
100
99.8
51.3
93.3
N.A.
89.6
86.7
N.A.
71.5
84.3
35.3
37.3
N.A.
45.8
N.A.
N.A.
52.4
P-Site Identity:
100
100
100
100
N.A.
93.3
93.3
N.A.
26.6
100
6.6
13.3
N.A.
0
N.A.
N.A.
53.3
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
33.3
100
20
40
N.A.
13.3
N.A.
N.A.
80
Percent
Protein Identity:
40.7
N.A.
N.A.
38.1
26.3
26.9
Protein Similarity:
58
N.A.
N.A.
56.2
46.3
46.4
P-Site Identity:
13.3
N.A.
N.A.
0
13.3
6.6
P-Site Similarity:
26.6
N.A.
N.A.
6.6
40
20
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
0
7
0
0
0
0
0
0
7
0
0
0
7
0
% A
% Cys:
0
0
0
0
0
7
0
0
0
0
0
7
0
0
0
% C
% Asp:
0
0
0
0
0
7
13
13
13
0
0
7
32
0
7
% D
% Glu:
13
7
0
13
7
7
7
0
0
0
0
7
13
13
0
% E
% Phe:
7
0
0
13
0
0
7
7
0
0
0
7
7
0
0
% F
% Gly:
0
7
13
0
0
0
0
0
0
0
0
7
7
0
13
% G
% His:
0
0
0
0
0
0
0
0
0
7
0
44
0
7
0
% H
% Ile:
0
7
0
7
0
7
0
0
0
0
0
7
0
0
0
% I
% Lys:
0
7
0
0
0
0
0
0
7
0
0
0
7
0
50
% K
% Leu:
57
7
0
0
63
57
0
13
7
13
57
7
7
13
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
13
0
7
7
57
7
0
0
13
7
0
0
0
% N
% Pro:
0
63
50
7
7
7
0
7
50
0
0
0
0
7
0
% P
% Gln:
0
7
7
50
0
0
13
0
0
0
13
0
0
44
13
% Q
% Arg:
0
0
0
7
0
0
0
0
0
25
0
0
0
13
7
% R
% Ser:
7
0
0
0
7
7
7
57
7
0
0
7
7
0
0
% S
% Thr:
0
0
7
7
0
0
0
0
0
7
7
0
0
0
0
% T
% Val:
13
0
7
0
13
0
0
0
13
0
7
0
13
0
7
% V
% Trp:
0
0
0
0
0
0
0
0
7
0
0
0
0
0
7
% W
% Tyr:
0
0
0
0
0
0
0
0
0
44
7
0
13
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _